Avoid concomitant use of herbal medicines and supplements
during treatment with fexinidazole.
- TRADE NAME: Fexinidazole (Sanofi)
- INDICATIONS: Treatment of both first-stage (hemolymphatic) and second-stage (meningoencephalitic) human African trypanosomiasis due to Trypanosoma brucei gambiense.
- SYNONYM: Fexinidazole Winthrop
- CLASS: Antimicrobial, Antiprotozoal
- FDA APPROVAL DATE: 07/16/2021
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Adefovir, Bupropion, Carbamazepine, Cefaclor, Clarithromycin, Diazepam, Dofetilide, Duloxetine, Efavirenz, Erythromycin, Fluconazole, Furosemide, Itraconazole, Lansoprazole, Lovastatin, Mephenytoin, Metformin, Midazolam, Nisoldipine, Phenytoin, Rifampin, Saquinavir, Simvastatin, St John's Wort, Tacrine, Theophylline, Tizanidine, Voriconazole - PREGNANCY: Insufficient to evaluate for a drug-associated risk of major birth defects or miscarriage.
- See adverse reactions attributed to class:
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Page last updated 08/20/2025
