Drug-induced disease

Many reports in the literature discuss aspects of drug-induced disease or injury which do not necessarily identify particular drugs or classes of drugs and their associated adverse drug reactions.

Such references might focus on the diagnosis, clinical pathology, pharmacology, pharmacogenomics or treatment of a drug-induced diseases or injury. Or analyse drug-induced diseases in relation to particular groups of the population (the young, the elderly, gender).

This area of the literature is accommodated in the Litt database under the category ‘Drug-induced disease (General)’ with further classification under the categories: skin; cardiovascular; central nervous system; endocrine/metabolic; gastrointestinal/hepatic etc. Litt’s weekly ‘Drug updates’ for subscribers lists ‘Drug-induced disease (General)’ as a separate heading with PubMed hyperlinks to references under these categories.

Drug-induced disease (Cardiovascular)

Drug-induced disease (Central Nervous System)

Drug-induced disease (Endocrine/Metabolic)

  • (2026): Liu W+, Naunyn Schmiedebergs Arch Pharmacol Apr, Online ahead of print [REVIEW] (hypercalcemia) (pharmacovigilance / pharmacoepidemiology)
  • (2026): Maese M+, BMC Res Notes Feb, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2026): Xi X+, Pak J Med Sci 42(4), 848-855 [REVIEW] (hyponatremia) (pharmacovigilance / pharmacoepidemiology)
  • (2026): Zhang P+, Naunyn Schmiedebergs Arch Pharmacol Mar, Online ahead of print [REVIEW] (hypokalemia) (pharmacovigilance / pharmacoepidemiology)
  • (2026): Zhao X+, Front Med (Lausanne) Jan (e-Collection) [REVIEW]Pediatric (pharmacovigilance / pharmacoepidemiology)
  • (2025): Ben Salem C+, Eur J Intern Med May, Online ahead of print (comment on Mannheimer B+, Eur J Intern Med, May 2025 (loc cit))
  • (2025): Borsari SF+, Praxis (Bern 1994) (German) 114(4), 149-153 [REVIEW] (adrenal insufficiency)
  • (2025): Capinha M+, J Clin Med 14(18), 6584 [REVIEW]
  • (2025): Ide N+, Drug Discov Ther Dec, Online ahead of print [REVIEW] (drug-induced weight gain) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Li R+, Endocr Pract Dec, Online ahead of print [REVIEW] (thyroid dysfunction) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Lv H+, Endocr Connect Dec, Online ahead of print [REVIEW] (diabetes insipidus ) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Mannheimer B+, Eur J Intern Med May, Online ahead of print [REVIEW] (hyponatremia)
  • (2025): Patel M+, Curr Atheroscler Rep 27(1), 52 [REVIEW]Pediatric
  • (2025): Song B+, Expert Opin Drug Saf Feb, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Song B+, BMC Pediatr 25(1), 515 [REVIEW]Pediatric (pharmacovigilance / pharmacoepidemiology)
  • (2025): Xi Y+, Andrology Sep, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Xiao S+, Endocr Metab Immune Disord Drug Targets Aug, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Yang H+, Front Pharmacol Apr (e-Collection) [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Yu X+, Diabetol Metab Syndr Oct (e-Collection) [REVIEW] (insulin autoimmune syndrome) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Zhang H+, Front Endocrinol (Lausanne) Nov (e-Collection) [REVIEW] (association) (pharmacovigilance / pharmacoepidemiology)
  • (2024): Ji X+, Expert Opin Drug Saf Sep, Online ahead of print (pharmacovigilance / pharmacoepidemiology)
  • (2024): Xiao Y+, Magnes Res 38(2), 56-69 [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2024): Yang X+, Clin Epidemiol 16, 617-630 (pharmacovigilance / pharmacoepidemiology)
  • (2012): Deepinder F+, Expert Opin Drug Saf 11(5), 779-95 [REVIEW]

Drug-induced disease (Gastrointestinal/Hepatic)

Drug-induced disease (Genitourinary)

  • (2026): Gong Z+, Front Pharmacol Jan (e-Collection) [REVIEW] (male infertility) (pharmacovigilance / pharmacoepidemiology)
  • (2026): Jin C+, Medicine (Baltimore) 105(3), e47250 [REVIEW]Pediatric (drug-induced urinary incontinence ) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Li C+, Sci Rep 15(1), 38278 (e-Collection) (urinary incontinence) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Tian X+, Sci Rep 15(1), 15760 [REVIEW] (erectile dysfunction) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Zheng G+, Sci Rep 15(1), 22856 [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2024): Dai X+, Front Pharmacol Jan (e-Collection) [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2024): Li D+, Expert Opin Drug Saf Aug, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2024): Moodley D+, Int J Impot Res Dec, Online ahead of print [REVIEW]
  • (2024): Zheng F+, Expert Opin Drug Saf 23(11), 1419-1426, Online ahead of print (pharmacovigilance / pharmacoepidemiology)
  • (2024): Zheng F+, Expert Opin Drug Saf Nov, Online ahead of print (pharmacovigilance / pharmacoepidemiology)

Drug-induced disease (Hair)

Drug-induced disease (Hematologic)

  • (2026): Ali SB+, Int Arch Allergy Immunol Mar, Online ahead of print [REVIEW]
  • (2026): Le BH+, Explor Res Clin Soc Pharm Apr (e-Collection) [REVIEW] (thrombocytopenia) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Lu Y+, Front Pharmacol Sep (e-Collection) [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Wen X+, Int J Clin Pharm 47(3), 755-766 [REVIEW] (hypofibrinogenemia) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Xia K+, Cancer Control May (e-Collection) [REVIEW] (myelosuppression) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Yin Y+, Front Pharmacol Sep (e-Collection) [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Zhang F+, Int J Clin Pharm 47(6), 1967-1978, Online ahead of print (pharmacovigilance / pharmacoepidemiology)
  • (2024): Lu Y+, Front Pharmacol Dec (e-Collection) [REVIEW] (coagulopathy) (pharmacovigilance / pharmacoepidemiology)
  • (2023): Mazzierli T+, Front Pharmacol Jan (e-Collection) [REVIEW]
  • (2019): Vo QT+, Ann Pharmacother 53(5), 523-536 [REVIEW] (Naranjo Adverse Drug Reaction Probability Scale or equivalent)

Drug-induced disease (Mucosal)

Drug-induced disease (Multi-Organ / Multi-Metabolic)

Drug-induced disease (Nails)

Drug-induced disease (Neuromuscular/Skeletal)

Drug-induced disease (Ocular)

Drug-induced disease (Other)

  • (2026): Karjalainen K+, Drug Alcohol Rev 45(1), e70083 [REVIEW]
  • (2026): Qiu Z+, Curr Med Chem Jan, Online ahead of print [REVIEW] (breast cancer) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Broe A+, Pharmacoepidemiol Drug Saf 34(9), e70211 [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Burckart GJ+, Clin Pharmacol Ther Nov, Online ahead of print [REVIEW] (pediatric safety)
  • (2025): Chen S+, Discov Oncol 16(1), 786 [REVIEW] (drug-induced second tumors) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Mai H+, J Affect Disord Dec, Online ahead of print [REVIEW] (congenital anomalies) (pharmacogenomics)
  • (2025): Matthias J+, Clin Transl Sci 18(11), e70406 [REVIEW] (pharmacogenomic interactions) (pharmacogenomics)
  • (2025): Mellou M+, Therapie Jul, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Rahurkar S+, Pharmacotherapy Oct, Online ahead of print [REVIEW]Pediatric (pharmacovigilance / pharmacoepidemiology)
  • Negative findings
  • (2024): Pivato CA+, Eur Heart J Dec, Online ahead of print [REVIEW] ("these findings suggest the cardiovascular safety of fertility treatments")
  • Negative findings
  • (2024): Zeng Y+, Andrology Oct, Online ahead of print (pharmacovigilance / pharmacoepidemiology)
  • (2023): Montastruc JL, Br J Clin Pharmacol 89(12), 3765-3768 [REVIEW] (bruxism) (pharmacovigilance / pharmacoepidemiology)

Drug-induced disease (Otic)

  • (2026): Narasimhaswamy N+, Naunyn Schmiedebergs Arch Pharmacol Jun, Online ahead of print [REVIEW] (tinnitus) (pharmacovigilance / pharmacoepidemiology)
  • (2026): Salvi R+, Hear Res Jul (e-Collection) [REVIEW] (hyperacusis) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Wu T+, Hear Res Apr, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2024): Li B+, Front Pharmacol Nov (e-Collection) (pharmacovigilance / pharmacoepidemiology)
  • (2021): Maia NPD+, Int Braz J Urol 47(4), 747-752 [REVIEW]

Drug-induced disease (Renal)

Drug-induced disease (Respiratory)

  • (2026): Algabbani AM+, Sci Rep Apr, Online ahead of print [REVIEW] (interstitial lung disease) (pharmacovigilance / pharmacoepidemiology)
  • (2026): Hu J+, Front Med (Lausanne) Apr (e-Collection) [REVIEW] (eosinophilic pneumonia) (pharmacovigilance / pharmacoepidemiology)
  • (2026): Poveda JJR+, Pulm Ther Jan, Online ahead of print [REVIEW] (drug-induced interstitial lung disease)
  • (2026): Rui Y+, J Thorac Dis 18(4), 364 [REVIEW] (pulmonary embolism) (pharmacovigilance / pharmacoepidemiology)
  • (2026): Zhao Y+, Front Med (Lausanne) Jun (e-Collection) [REVIEW] (acute respiratory distress syndrome ) (pharmacovigilance / pharmacoepidemiology)
  • (2025): Cui Y+, Respiration Oct, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): He Y+, Sci Rep 15(1), 23937 [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Kamath A, Sci Rep 15(1), 1455 (pharmacovigilance / pharmacoepidemiology)
  • (2025): Rui Y+, Respir Med Sep, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Vanhandsaeme G+, Respiration Nov, Online ahead of print [REVIEW] (drug-induced interstitial lung disease)
  • (2025): Wang E+, Expert Opin Drug Saf Mar, Online ahead of print [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Yamanaka M+, Respir Investig 63(4), 524-531 [REVIEW]
  • (2025): Yayan J+, J Pharm Health Care Sci 11(1), 60 [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2025): Zhong Z+, Braz J Med Biol Res Aug (e-Collection) [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2024): Annareddy S+, Cureus 16(9), e69954 [REVIEW]
  • (2024): Butranova OI+, Biomedicines 12(12), 2650 [REVIEW] (pharmacovigilance / pharmacoepidemiology)
  • (2024): Cörüt R+, Cureus 16(6), e63408 (20 cases)
  • (2024): Shen Y+, Int Immunopharmacol Jun, Online ahead of print [REVIEW]
  • (2024): Shroff GS+, Clin Chest Med 45(2), 325-337 [REVIEW]
  • (2020): Hayashi R+, Anesth Prog 67(4), 214-218 (1 case / male)

Drug-induced disease (Skin)