Granulocyte Colony-Stimulating Factor (G-CSF)
BreastfeedingPediatric

  • TRADE NAMES: Filgrastim; Granix (Sicor); Grasin; Leucogen; Leukine (Bayer, Berlex); Neulasta (Amgen); Neupogen (Amgen); Neupogen 30; Pegfilgrastim; Prokine; Zarxio (Novartis)
  • INDICATIONS: Bone marrow allograft and autograft
  • SYNONYM: filgrastim; sargramostim; pegfilgrastim; mecapegfilgrastim (pegfilgrastim biosimilar)
  • CLASS: Biologic, Colony stimulating factor, Covid-19 putative drug, Hematopoietic
  • HALF-LIFE: filgrastim: 3.5 hours; sargramostim: 2–3 hours; pegfilgrastim: 15–80 hours; tbo-filgrastim: 3–4 hours
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    Fluorouracil

Investigated for treating COVID-19.

rGM-CSF is granulocyte-macrophage colony-stimulating factor; rG-CSF is granulocyte colony-stimulating factor.

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Page last updated 09/24/2025

Symbol key

Incidence - Help

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness - Help

Hospitalization possible
Life threatening
Fatal

Warnings in other populations - Help

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric

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