Children appear to be at higher risk for complications than adults when using intrathecal baclofen (ITB). ITB therapy is a safe and effective treatment for severe spasticity in the pediatric population, but does have a 31% rate of complications requiring surgical management over a 3-year treatment period.
- TRADE NAMES: Baclofen (Watson); Baclon; Baclosal; Baklofen; Clofen; Dom-Baclofen; Gablofen (Mallinckrodt); Gen-Baclofen; Lebic; Lioresal (Medtronic); Nu-Baclo; Pacifen; PMS-Baclofen; Spinax
- INDICATIONS: Spasticity resulting from multiple sclerosis
- CLASS: GABA receptor agonist, Skeletal muscle relaxant
- HALF-LIFE: 2.5–4 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Acebutolol, Alcohol, Alfuzosin, Amitriptyline, Captopril, Cilazapril, Diclofenac, Enalapril, Fosinopril, Irbesartan, Levodopa, Lisinopril, Meloxicam, Olmesartan, Quinapril, Ramipril, Trandolapril
DO NOT DISCONTINUE ABRUPTLY
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Page last updated 08/20/2025
