Contra-indicated in patients with hereditary/idiopathic angioedema and in patients with a history of angioedema related to previous treatment with an ACE inhibitor.
Tarka is trandolapril and verapamil.
- TRADE NAMES: Gopten; Mavik (AbbVie); Odrik; Tarka (AbbVie); Udrik
- INDICATIONS: Hypertension
- CLASS: Angiotensin-converting enzyme (ACE) inhibitor, Antihypertensive, Vasodilator
- HALF-LIFE: 6 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Alcohol, Aldesleukin, Aliskiren, Allopurinol, Alpha blockers, Amiloride, Angiotensin II receptor antagonists, Antacids, Antidiabetics, Antipsychotics, Anxiolytics and hypnotics, Baclofen, Beta blockers, Calcium channel blockers, Clonidine, Corticosteroids, Cyclosporine, Diazoxide, Diuretics, Estrogens, General anesthetics, Gold & Gold Compounds, Heparins, Hydralazine, Insulin, Levodopa, Lithium, MAO inhibitors, Metformin, Methyldopa, Minoxidil, Moxisylyte, Moxonidine, Nitrates, Nitroprusside, NSAIDs, Potassium salts, Spironolactone, Sulfonylureas, Tizanidine, Triamterene, Trimethoprim - PREGNANCY: category C in first trimester; category D in second and third trimesters
- See adverse reactions attributed to class:
FETAL TOXICITY
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Page last updated 08/20/2025
