Although trimethoprim has been known to elicit occasional adverse reactions by itself, it is most commonly used in conjunction with sulfamethoxazole (co-trimoxazole - see separate entry).
- TRADE NAMES: Abaprim; Alprim; Bactin; Bactrim (Women First); Idotrim; Ipral; Lidaprim; Methoprim; Monotrim; Polytrim; Primosept; Primsol; Septra (Monarch); Syraprim; Tiempe; Trimopan; Triprim; Unitrim
- INDICATIONS: Various urinary tract infections caused by susceptible organisms, acute otitis media in children, acute and chronic bronchitis
- CLASS: Antibiotic, Antimicrobial
- HALF-LIFE: 8–10 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
ACE inhibitors, Amantadine, Angiotensin II receptor antagonists, Antidiabetics, Azathioprine, Benazepril, Captopril, Carvedilol, Cilazapril, Conivaptan, Coumarins, Cyclosporine, CYP2C8 substrates, CYP2C9 inhibitors, CYP3A4 inducers, Dapsone, Deferasirox, Digoxin, Dofetilide, Enalapril, Eplerenone, Fosinopril, Irbesartan, Lamivudine, Leucovorin, Levoleucovorin, Lisinopril, Memantine, Mercaptopurine, Metformin, Methotrexate, Olmesartan, Oral typhoid vaccine, PEG-Interferon, Phenytoin, Pioglitazone, Pralatrexate, Procainamide, Pyrimethamine, Quinapril, Ramipril, Repaglinide, Rifampin, Sulfonylureas, Trandolapril
- See adverse reactions attributed to class:
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Page last updated 08/20/2025
